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REPRESENTATION OF HER2 FAMILY For Dako Corporation. Text from HercepTest™ Pathology Interpretation Manual: "...Activation of HER family members occurs when the ligand and a dimer of the same monomer or other member of the HER family are bound together. Once activation has occurred, tyrosine autophoshorylation of cytoplasmic signal proteins transmit signals to the nucleus, thus regulating aspects of cell growth, division, differentiation and migration." Copyright 2008 Dan Futoran. Do not copy. All rights reserved. |